Enhancing T cell affinity discrimination to reduce the cross-reactivity of T cell therapies

Title: Enhancing T cell affinity discrimination to reduce the cross-reactivity of T cell therapies.

 

Bio: Jose received His BSc in Biological Sciences at the University of Edinburgh, before moving to the University of Oxford to pursue a DPhil in Interdisciplinary Bioscience. He joined the group of Omer Dushek to study T cell cross-reactivity, where he continued to work as a postdoctoral researcher.

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How much labelled training data do we need to predict TCR specificity against private neoantigens?

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Exploring Human T cells and TCRαβ repertoire at the single-cell level