Exploring Human T cells and TCRαβ repertoire at the single-cell level
Bio:
Dr. Wanlu Liu is a tenured associate professor and assistant dean at the Zhejiang University-University of Edinburgh Joint Institute, Zhejiang University. She also serves as an honorary lecturer at the University of Edinburgh and as an adjunct researcher in the Department of Rheumatology and Immunology at the Second Affiliated Hospital of Zhejiang University. Dr. Liu earned her Bachelor of Medicine from Zhejiang University and her PhD from UCLA. Her research focuses on bioinformatics and computational immunology, particularly in developing databases and AI algorithms for single-cell and spatial omics to investigate the phenotypic and functional diversity of T cell receptors (TCRs). She has published research papers in Cell, Nature Methods, Nature Communications, and Nucleic Acids Research. Dr. Liu leads projects funded by the National Natural Science Foundation of China and is an active member of the Immune Cell Biology Branch of the Chinese Society for Cell Biology and serves on the committee of the Zhejiang Bioinformatics Society.
Outline:
Introduction to huARdb, a online web database to explore single-cell TCR-seq data
Integrative mapping of million-scale human CD8 T cells with in cancer and inflammation