Engineering T Cell Recognition: From Antigen Discovery to Programmable Immunotherapy
Why do many cancers remain invisible to the immune system? In this webinar, Dr Nicholas Sgourakis explores how engineered MHC chaperones and protein engineering strategies can expand antigen presentation and reveal hidden tumour targets, opening new paths toward programmable and broadly applicable cancer immunotherapies.
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Unconventional lipid-antigen recognition by group 1 CD1-restricted T cells
How do T cells recognise lipid antigens beyond classical peptide–MHC pathways? In this webinar, Dr Adam Shahine explores emerging mechanisms of antigen presentation by group 1 CD1 molecules, highlighting structural insights into CD1–TCR interactions and recent discoveries in CD1c-mediated lipid antigen recognition.
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