Episode 3 - Dr Agne Antanaviciute: AI Uncovers the Cellular and Molecular Basis of Perianal Crohn’s Fistulas

Perianal fistulas are among the most debilitating complications of Crohn’s disease, yet their underlying biology has remained poorly understood.

In this episode of Immunity by Design, Prof Hashem Koohy speaks with Dr Agne Antanaviciute about how cutting-edge single-cell genomics, spatial transcriptomics, and artificial intelligence are transforming our understanding of fistula biology.

Together they discuss how machine learning is helping identify the cellular interactions, immune pathways, and molecular mechanisms that drive chronic inflammation and tissue remodelling, opening new possibilities for precision diagnostics and targeted therapies.

Whether you are a researcher, clinician, or simply interested in the future of AI in medicine, this episode offers an accessible overview of one of the most exciting developments in computational immunology.